Patriot vs. Cardinals odds, spread, line: Monday Night Football picks, NFL predictions from proven model

Teams looking for a two-game losing streak will clash when the New England Patriots meet the Arizona Cardinals in a major interconference game on Monday Night Football. The Patriots (6-6), one game away from the final Wild Card spot in the AFC playoff picture, dropped a 24-10 decision to the Buffalo Bills last Thursday. The Cardinals (4-8), who are on the verge of the NFC playoff picture, lost 25-24 to the Los Angeles Chargers two weeks ago before bidding their farewells. New England has won the last two matchups with Arizona.

Kickoff at State Farm Stadium in Glendale, Ariz., is scheduled for 8:15 p.m. ET. New England is a 1.5-point favorite in the latest Patriots vs. Cardinals from Caesars Sportsbook, while the over/under for total points scored is 43.5. Before you watch Cardinals vs. Patriots picks or NFL betting, you need to view the NFL predictions from the SportsLine projection model.

The model, which simulates every NFL game 10,000 times, has soared more than $7,000 for $100 players on top-rated NFL picks since its inception. The model heads into week 14 of the 2022 NFL season with an incredible 156-112 run on top-rated NFL picks dating back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on regular NFL picks, beating over 94% of CBS Sports Football Pick’em players four times in that span. Anyone who has followed it is a way up.

Now the Patriots vs. Cardinals by MNF broken down. You can go to SportsLine to see the choices. Here are the NFL lines and trends for Cardinals vs. patriots:

  • Spread of patriots vs. cardinals: New England -1.5
  • Patriot vs. Cardinals over/under: 43.5 points
  • Moneyline Patriots vs. Cardinals: Patriots -125, Cardinals +105
  • NE: Patriots are 12-2 on spread in their last 14 games after a double-digit home loss
  • ARI: Cardinals are 5-2 ATS in their last seven games after an outright loss
  • Patriot vs. Cardinals picks: See picks on SportsLine

Recommended game | Arizona Cardinals vs New England Patriots

Why the Patriots can cover

Quarterback Mac Jones completed 184 of 270 passes (68.1%) for 1,963 yards and seven touchdowns for an 87 rating. He also rushed for a score and hasn’t thrown a pick since October 30. and during a Thanksgiving night loss at Minnesota, Jones completed 28 of 39 passes (71.8%) for 382 yards and two touchdowns for a rating of 119.8. In last Thursday’s loss to the Buffalo Bills, he completed 22 of 36 passes (61.1%) for 195 yards and one touchdown.

Wide receiver Jakobi Meyers is his main target. Meyers has 50 receptions for 593 yards (11.9 average) and three touchdowns. He has three explosive plays of 20 yards or more, including a 30-yarder. Meyers has 167 yards on the catch and has converted 28 first downs. He has two nine-catch appearances, including nine receptions for 60 yards and a score in a win at the New York Jets on Oct. 30. See which team to choose here.

Why the Cardinals can cover

Despite this, the Patriots are not a lock on the spread of Patriots vs. Cardinals cover. That’s because Arizona has a dual-threat quarterback in Kyler Murray, who leads the team in passing, completing 258 of 389 attempts (66.3%) for 2,359 yards and 14 touchdowns. He has seven interceptions and a rating of 87.1. Murray is also the team’s second-leading rusher, with 66 runs for 415 yards (6.3 average) with three big plays, including a 42-yarder, and three touchdowns. He also converted 23 first downs.

One of his many options is wide receiver DeAndre Hopkins. In just six games, Hopkins is tied for the team lead with 49 receptions for 574 yards (11.7 average) and three touchdowns. He has seven big plays, including a season-long 33-yarder. He has 126 yards on the catch and also converted 27 first downs. In a 27–17 win at the Los Angeles Rams on November 13, Hopkins had 10 catches for 98 yards. He also had 12 catches for 159 yards and one touchdown in Minnesota on October 30. See which team to choose here.

How Cardinals vs. making Patriots picks

The model has captured the match between Patriots vs. Monday Night Football’s Cardinals snapped from all angles. It leans below the total, with the model sticking out 42 points combined. It also says that one side of the spread hits more than 50% of the time. See who it is at SportsLine.

So who will win Cardinals vs. Patriots on Monday Night Football? And which side of the spread hits more than 50% of the time? Visit SportsLine now to find out which side of the Cardinals vs. Patriots spread you should be all over the place, all from the model on a roll of 156-112 to his top-rated NFL picks, and find out.

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